Rupture of Membranes

In the past over 5yrs ago we used Amnisure as a test for rupture of membranes.  We eliminated the test when we started getting erroneous results.  We now have several new OB/GYN providers that are looking to bring back some sort of testing for ROM.  So I am turning to the masses to find out what others are using for their testing.  If you could let me know what you are currently using and the pros and cons as you see it for your method it would be greatly appreciated.   Thanks

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Nitrazine paper and Fern testing.


Susan L. Alford

Laboratory Point of Care Coordinator

Nanticoke Health Services

801 Middleford Road

Seaford, DE 19973

Phone: 302-629-6611 Ext. 2560

Fax: 302-628-6352

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We have used Amnisure and Nitrazine pH tesing for years, without erroneous results.  We are looking at switching to Fern Testing (which has awful results) due to insurance providers declining the Amnisure as Experimental.

We have the Amnisure now and a few providers perform Fern testing. We are about to trial Actim-Prom as it is cheaper, is not affected by blood, gels, powders etc. The nurses really wanted Actim-Prom due to only having to insert the swab vaginally for 10-15 seconds instead of 1 minute for Amnisure. We will see what the coorelation study looks like.

We currently use Amnisure, but we don't do it entirely POC. We were having issues with nursing staff not entering test results in the patient chart, so we switched to having nurses collect the specimen and send it to the lab for the actual test. We haven't really had any issues with testing since then.

I spoke with a rep about Actim PROM, but we opted not to look too much into switching due to the limitations on gestational age (>/= 29 weeks only). They are approved in other countries for all gestational ages but are waiting on clearance in the US.

We validated an ROM test in the lab all of my labs with an L/D unit. It used to be Aminsure...but we then validated another one that is cheaper.

We removed the pH swabs at the time the kits were validated in the lab. Reimbursement is good and we have had no issues with it.

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