Possible Heparin Reactivity Issue Causing Discrepant ACT results in Cath Lab

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Our cardiologists have told us that the ACT results on the i-STAT are discrepant, but then mentioned that there was also a possible problem with the reactivity of the heparin being used nationwide.  Of course, they couldn't tell us which patients were involved.  We're having them document the lot number of heparin that is being used, in addition to notifying us when the situation occurs.


Has anyone heard of any problems with heparin reactivity or had any problem with discrepant ACT testing on the i-STAT recently?


Thanks!


Linda

64 Replies

Hi Ashlee, would love to look at it as well : annalyn.gemmell@pennmedicine.upenn.edu


Thank you!

Sorry I forgot that!  Here you go:  linda.kuhn@osfhealthcare.org


Thanks!

We have had the same issue and use the Medtronic ACT Plus.  The compliant was they feel like they are pushing a lot more heparin before the see the anticipated response.


We have found that our pharmacy was using different lots of heparin from different countries-India v. China.  Also there seemed to be a timing issue of when the patient was given a bolus of heparin and when the ACT was drawn/tested.


Have not heard much else after.


Ashlee,


I would love to see your study. We’re considering changing from Hemochron to I-Stat ACT-K.


Thanks!


Cecilia.haddock@tenethealth.com


Has anyone had this problem with the Hemochron Sig Elite analyzer? Can someone please send me the study? We are having issues using the ACT-LR cuvette only during vascular procedures. Surgeons not confident in the analyzer.


Thank you in advance for your help.


Claudia Leblanc


Portsmouth Regional Hospital


Portsmouth, NH 

Ashee,


I would love to see your study.


Thanks! 


cynthia.hollis@eastgeorgiaregional.com

Just curious, what is the driver for the change in ACT methodology?

I would also love a copy of study


 


Thanks in advance


Health Care Authority of Anniston


Anniston, Alabama


galabynum@aol.com


or


gbynum@rmccares.org


Ashlee,


I’d love to have a copy of your study. Thank you in advance.


 


Claudia.leblanc@hcahealthcare.com


Thanks to this listserve, we made contact with our pharmacy.  They are aware of the heparin shortage potential and was already keeping 4-6 month supply and checked with their supplier to see if they will be having a shortage.  They will also let lab know if they change suppliers so we can proactively work with our IR, Dialysis Cathlab and ECMO teams.


Thanks for the heads up!


Reine Makiya

Thank you for the info - I too would like a copy of your study. e.precissi@dameronhospital.org . We use Hemochron sig elite ACT+ and there have been a two cases now where I have received a complaint that the ACT did not respond as the physician expected to the heparin dosage given . These were 'Impella' patients - a new procedure to our facility.

Hi Ashlee,


Could I please have a copy of your study as well? jlhay@lhs.org


Thank you!


It is time to replace devices and our affiliated sister hospitals use I-Stat so I leaned toward standardization.


But, I read a lot, talked with other users, and communicated with physicians.


copy for me too please!


deatone@bronsonhg.org


Thanks soooo much!


Erika Deaton-Mohney

Ashlee,


Please send me a copy of the study you did.


My email: PManiquis@primehealthcare.com


Thanks,

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Linda Kuhn
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