Pediatric hospitals using iSTAT for ACTs

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  Hello Everyone!


 A colleague of mine on the AACC Artery was interested in Pediatric ACT reference ranges/ guidelines that you use for celite ACT cartridges for iSTAT. They are switching over from Hemochron Response and because the methods are very different, they have differences of 45 seconds which the clinicians are not comfortable with.


 Thanks


 Adil


 ----------------------------------------


 Associate Professor of Pathology
Director, Point of Care Testing
Temple University & Episcopal Hospitals
Director, Clinical Chemistry


Temple University Episcopal Hospital  



& NACC Laboratories


 Tel:     215-707-0965
Fax:    215-707-0966
Cell:   267-908-2114

12 Replies

I'm interested in other pediatric hospitals experience with iSTAT ACT. We currently use Medtronic ACT plus. I guess they tried to switch over years ago but there was too much difference at the low range, especially for ECMO. I'd really like to see the Medtronic device go away just so we could have most of our testing on one instrument.

Hi,


We use Hemochron Signature Elite LR (Low Range) cuvettes for our Cathlab, ECMO, Dialysis and Interventional Radiology patients.  They run a baseline ACT before administering heparin and go from there.


Thanks,


Reine

We use the iSTAT celite cartridge for pediatric ECMO patients.  We did most correlations to the Hemachron Response and it was quite close (about 8% bias).  I did a smaller correlation with it against the HMS and they were close then too but that was in a Cath Lab population.  It's very difficult to switch platforms for ACT since it usually requires a change in their target values and it is a challenge to get the care team to understand it is due to different methodology rather than an "inaccurate" instrument.

I did a large study at my last employer comparing Hemochron Jr, Hepcon, Hemochron Response, iSTAT ACTk - PREWARM, and iSTAT ACTk - NONWARM. 


I found that the iSTAT in NONWARM mode matched the Hemochron Response tube method very well. All of the studies done in the 70's about ACT used the tube method - therefore nearly all of the original published target ranges were based off of that method. I changed all of my sites to NONWARM and we no longer needed to have a conversion table for the doctors.


Here at Children's Hospital Colorado we only use iSTAT ACTk for ECMO, Cath and CVOR.

Silka, that is great info! I'm just starting to think about this and it's great to know those details. Obviously it will be a huge learning curve to change methods.

Yep! I am always happy to share my study with anyone that would like to see the powerpoint I did. It was quite a few years ago now, but the info still stands the same since we are all still working with the same technology :) 


 

Hi Silka,


We have several iSTATs and a a couple of Hepcons. We recently acquired a Hemochron and I am interesting to see your PPT presentation to get ideas on how to validate the Hemochron. You can email it to pcastan1@fairview.org


I will appreciate very much!


Thank you!


Pedro

Hi Silka,


I would like to see your PPT presentation.  My email is woodwars@musc.edu


My hospital currently uses iSTAT for ACT, the perfusion team is interested in Hemochron.


Thanks so much!

Hi Silka


I would like to see your PP presentation. My e mail is nubiawood1@gmail.com


Thanks a lot


Nubia Wood

Please email to danyel.olson@childrensmn.org


Thanks!

Hi Silka,


Please email to sclark@mercydesmoines.org.


Thank you!


 

Hi Silka,


I would love to see this PPT.  Please email me at danielle.ennis613@gmail.com


Thanks!

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Adil Khan
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