High Sensitivity Troponin on iSTAT

20 followers

0 Likes

Hello everyone,

My site is currently working on creating an Epic build for the NEW high sensitivity troponin cartridge, but there is no plan in place as this is very new for POC. I requested that two order codes be built, one that is interfaced through RALS into our LIS and one for manual entry. We are hitting roadblocks with needing a RALS upgrade and mirth conversion to interface this cartridge. Has anyone started their LIS order build for this cartridge yet? I am questioning delta calculations and gender specific reference ranges. I would love to chat and get a better grasp on which way I should be leading this new build. I am also open to discussions regarding what everyone is doing for their validation studies.

Please reach out if you have any insight!

Ashley Kopp
732-836-4787
ashley.kopp@hmhn.org

5 Replies

Kathleen David

Thu Jul 17, 2025 at 4:38PM

We are also looking at bringing on the i-STAT hs-troponin. We have Telcor, and I don't think we have any issues with the build. My question is about how everyone is handling the protocol for interpreting results. We have Roche hs-troponin T on our lab instrumentation, and i-STAT is hs-troponin I. We are working on what we will use for our cutoffs for results--rule in or rule out. There isn't any literature out there yet, since this is so new. Does anyone have this set up yet? Any ideas are welcome.
kathleen.david@tricore.org

Tim Tarrant

Thu Jul 17, 2025 at 4:51PM

You could do a clinical concordance study. Test acute chest-pain specimens simultaneously on the i-STAT hs-cTnI and Roche hs-cTnT assays. Then compare each result to its assay-specific 99th-percentile cutoff and calculate the positive and negative agreement.

Cathy Cannon

Thu Aug 14, 2025 at 12:55PM

Has anyone gone live with the hs-Troponin i-STAT cartridge? If so how have you integrated the test in the patient work-up?

Tracie Popejoy

Tue Aug 26, 2025 at 12:19PM

We are wrapping up our validation and I wondered how anyone else's looks? We are comparing the i-STAT hsTrop to the Beckman hsTrop (been in use for quite awhile now). I was also wondering what sort of comment anyone is adding the i-STAT result indicating the testing/cut-off differences and/or the difference from in-lab testing? Also any physician education happening? Any conversation on what anyone else is doing would be greatly appreciated.

Thanks-
Tracoe
tracie.popejoy@promedica.org

Lindsey Scanlon

Wed Dec 03, 2025 at 1:27PM

With those of you who have successfully completed the validation process, would you be willing to share any of your process to those of us who are just starting? I ordered a bulk supply of the cTnI cartridges to tide us over until we wrapped up with a previous project, so we're in the beginning phase of validations. Thank you in advance to those who would be willing to lend any support.

Subgroup Membership is required to post Replies

Join POCT Listserv now

Topic	Replies	Views	Participants	Last Reply
POC ammonia test Jake Fray 2 days ago	0	161		Jake Fray 2 days ago
Glucose Meter Strip Validations Adelina Wright 2 days ago	4	320	+ 1 more	Jeremy MacDonald 2 days ago
FOB - moving away from POC Brian Castle 3 days ago	10	488	+ 3 more	Jeremy MacDonald 2 days ago

Setup Information

High Sensitivity Troponin on iSTAT